高血压病患者心率变异减低与动态血压的关系

目的:旨在探讨高血压患者心率变异减低与动态血压的关系。方法:按照1978年WHO 标准选取高血压病患者48例及正常人36例。所有受试者在一周内分别作动态血压监测及动态心电图心率变异分析。结果:高血压病患者 HRV 明显低于正常人,血压昼夜节律消失者在高血压Ⅰ期患者中占21.4%、Ⅱ期患者中占50%、Ⅲ期患者中占81.3%,高血压病患者平均动脉压与 HRV 呈负相关。结论:高血压病患者血压升高与 HRV 减低及血压昼夜节律消失具有内在联系。高血压病患者存在自主神经功能障碍,自主功能损害程度与高血压病病情有关。

Decreased Heart Rate Variability and Its Association with Ambulatory Blood Pressure in Patients with Essential Hvpertention

Objective:To explore the decreased heart rate variability(HRV)and its association with ambulatory blood pressure(ABP)in patients with essential hypertention.It has been proved that HRV signals contain the activity information of cardiovascular regulation system.The connection of the de- creased HRV with ambluatory blood pressure has not been studied.Methods:Forty-eight patients with es- sential hypertention was selected according to WHO standard.ABP monitoring and HRV through ambula- tory electrocardiography were studied within 7 days in the patients and in normal controls.Results:In the patients with essential hypertention,the HRV was lower by comparison with normal controls.Blood circan- dian variation vanished gradually according to grade Ⅰ,grade Ⅱ,and grade Ⅲ.Mean arterial pressure (MAP)had a tendancy to associate negativly with HRV.Conclusion:The decreased HRV is associated with the elevation of blood pressure as well as the blood pressure circandian variation disappear andauto- nomic nerve dysfunction exists and the disturbance degree associated with the state of illness in the pa- tients with essential hypertention.