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复方鲜竹沥液的工艺改进
引用本文:肖红兵,谢彦兵,李海兵,刘卫萍,刘永学.复方鲜竹沥液的工艺改进[J].国际药学研究杂志,2012,39(4):345-346.
作者姓名:肖红兵  谢彦兵  李海兵  刘卫萍  刘永学
作者单位:肖红兵 (中国人民解放军第一八四医院药械科,江西鹰潭,335000) ; 谢彦兵 (中国人民解放军第一八四医院药械科,江西鹰潭,335000) ; 李海兵 (中国人民解放军第一八四医院药械科,江西鹰潭,335000) ; 刘卫萍 (军事医学科学院放射与辐射医学研究所药理毒理室,北京,100850) ; 刘永学
摘    要:目的改进复方鲜竹沥液制剂处方中薄荷油的添加工艺,得到澄清、质量合格的制剂。方法利用吐温-80的增溶作用,提高薄荷油的溶解性。将薄荷油加入吐温-80中,充分混匀后加至鲜竹沥药中充分搅拌、过滤,即得澄清制剂。结果制剂澄清,质量合格。结论该方法可行,工艺简单而稳定,更适合生产企业。

关 键 词:复方鲜竹沥液  薄荷油  吐温-80  工艺

Technical improvement in the preparation of Fufang Xianzhuli oral liquid
XIAO Hong-bing,XIE Yan-bing,LI Hai-bing,LIU Wei-ping,LIU Yong-xue.Technical improvement in the preparation of Fufang Xianzhuli oral liquid[J].Foreign Medical Sciences(Section of Pharmarcy),2012,39(4):345-346.
Authors:XIAO Hong-bing  XIE Yan-bing  LI Hai-bing  LIU Wei-ping  LIU Yong-xue
Institution:1.Department of Pharmacy,The 184th Hospital of PLA,Yingtan 335000,China;2.Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850,China)
Abstract:Objective To obtain a better qualified oral liquid preparation of Fufang Xianzhuli by improving addition methods of the peppermint oil.Methods Tween-80 was used to improve the solubility of peppermint oil in the experiment.Peppermint oil was mixed with Tween-80 sufficiently.Then the admixture was put into the physic liquor of Xianzhuli and agitated sufficiently.After that,the physic liquor was filtered and the clear preparation was obtained.Results The preparation was clear and qualified.Conclusion The new method is simple,stable and more suitable for improving the solubility of the peppermint oil.
Keywords:Fufang Xianzhuli oral liquid  peppermint oil  Tween-80  technique
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