| 升麻地上部分新的三萜皂苷类成分 |
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| 引用本文： | 潘瑞乐,陈迪华,斯建勇,赵晓宏,沈连钢.升麻地上部分新的三萜皂苷类成分[J].中国中药杂志,2003,28(3):230-232. |
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| 作者姓名： | 潘瑞乐 陈迪华 斯建勇 赵晓宏 沈连钢 |
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| 作者单位： | 中国医学科学院,中国协和医科大学,药用植物研究所,北京,100094 |
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| 摘 要： | 目的 :从升麻Cimicifugafoetida地上部分寻找新的天然活性成分。 方法 :利用多种色谱技术进行分离纯化 ,根据理化性质和现代波谱技术并辅以化学方法进行结构鉴定。结果 :从升麻地上部分 80%乙醇提取物的乙酸乙酯部分分得 4个9,19 环菠萝蜜烷型三萜皂苷 ,分别鉴定为 :西麻苷Ⅲ (1) ;25-O-乙酰升麻醇木糖苷 (2 ) ;25-O-乙酰升麻醇半乳糖苷 (3) ;7β-羟基升麻醇木糖苷 (4)。 结论 :1为新化合物 ,4是首次从该植物中分得。
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| 关 键 词： | 毛茛科 升麻地上部分 西麻苷Ⅲ |
| 文章编号： | 1001-5302(2003)03-0230-03 |
| 收稿时间： | 2002/8/25 0:00:00 |
| 修稿时间： | 2002年8月25日 |
Studies on the New Triterpenoid Saponin of the Aerial Part of Cimifuga foetida |
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| PAN Rui le;CHEN Di hua;SI Jian yong;ZHAO Xiao hong;SHEN Lian gang.Studies on the New Triterpenoid Saponin of the Aerial Part of Cimifuga foetida[J].China Journal of Chinese Materia Medica,2003,28(3):230-232. |
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| Authors: | PAN Rui le;CHEN Di hua;SI Jian yong;ZHAO Xiao hong;SHEN Lian gang |
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| Institution: | Institute of Medicinal Plant, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100094, China. |
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| Abstract: | OBJECTIVE: To find new active constituents from the aerial part of Cimicifuga foetida. METHOD: Various column chromatographic techniques were used for the isolation and purification of the principles. The structures were elucidated on the basis of spectral data and chemical evidences. RESULT: Four 9,19-cycloartane triterpenoid saponins were obtained and identified as Cimifoetiside III (25-anhydrocimigenol-3-O-beta-D-galactopyranoside, 1), 25-O-acetyl-cimigenol xylopyranoside (2), 25-O-acetyl-cimigenol galactopyranoside (3), 7 beta-hydrocimigenol xylopyranoside (4). CONCLUSION: Compound 1 is new and compound 4 was isolated from this plant for the first time. |
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