Kinin formation in the plasma and cerebral blood flow under conditions of cerebral ischemia/reperfusion in rats during modulation of kinin system activity |
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| Authors: | M. V. Orobei V. P. Kulikov Y. G. Shatillo |
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| Affiliation: | (1) Department of Pathophysiology, Altai State Medical University, Barnaul, Russia |
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| Abstract: | Suppression of kininogenesis is an adaptive phenomenon in cerebral ischemia/reperfusion in rats aimed at elimination of the no-reflow phenomenon. Hyperkininogenesis and suppression of kinin destruction are pathogenetically significant, because they augment the manifestations of no-reflow phenomenon during reperfusion following ischemia. __________ Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 146, No. 7, pp. 30–32, July, 2008 |
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| Keywords: | ischemia reperfusion brain cerebral bloodflow kallikrein |
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