小儿肺炎支原体感染的实验检测

目的 探讨郑州市肺炎支原体（MP）致小儿感染的流行情况，为诊治和预防工作提供资料。方法 应用ELISA法检测疑似呼吸道感染患儿，急性期血清中7种病原体特异性lgM抗体，为临床提供病原学依据。结果 从8549例被检血清中，检出7种病原体相关lgM抗体阳性2907例。其中MP—lgM抗体阳性708例，占总阳性的24．35％（居第2位），含单-感染523例，混合感染185例。临床除显示呼吸系统病变外，尚有呼吸道外多系统病变者占8．3％。结论 MP已为该地致小儿呼吸道疾病的重要病原体。常年均有小儿感染发病．以冬春季为流行高峰，学龄前儿童易感率高，〉6岁后则明显下降。对MP感染者，需同时要密切观察肺内和肺外多系统发生的病变，以防漏诊误治。

Laboratory Test of Mycoplasma Pneumonia(MP)Infection among children

Objective ] To explore the epidemic situation of children ＇s mycoplasma pneumonia （MP） infection in Zhengzhou. Methods] ELISA was applied to detect IgM antibody of 7 pathogens in the serum of suspected acute respiratory infected children and provide etiological evidence for the clinics. Results] 7 kinds of relative IgM antibody were detected in 2907 out of 8549 detected serum samples, among which 708 cases were MP-IgM antibody accounting for 24, 35% of the total positive rate and ranking the second place; 523 cases and 185 cases belonged to single infection and compound infection respectively; 8.3% of them also clinical- ly indicated non -respiratory pathological changes. Conclusion] MP has been an important pathogen for children＇s respiratory dis- eases in this area; MP infection takes place during the whole year with winter and spring as the epidemic peak; the preschool chil- dren are most susceptible but the morbidity decreases among the children over six years old; close observation should be made on the intrapulmonary and extrapulmonary pathological changes in order to prevention misdiagnosis.