间苯三酚联合缩宫素对需引产分娩的初产妇产程进展和分娩结局的影响

目的 探讨间苯三酚联合缩宫素应用对于需引产分娩的初产妇产程进展、产妇及新生儿分娩结局的影响.方法 选取2019年1月至2020年12月在合肥市第三人民医院需引产分娩的足月单胎初产妇60例,采用随机数字表法分为观察组与对照组,每组30例,对照组单用缩宫素治疗,观察组应用缩宫素联合间苯三酚治疗,收集产妇的产程进展、产后出血量、宫颈或阴道裂伤发生率、产时羊水Ⅲ度发生率、阴道分娩率和新生儿Apgar评分等,并对两组数据进行比较.结果 观察组第一产程、总产程时间分别为(407.9±125.4)min、(450.5±131.0)min,均显著短于对照组的(663.3±218.2)min、(722.1±223.4)min(P<0.05).两组阴道分娩率、产后出血量、宫颈或阴道裂伤发生率、产时羊水Ⅲ度发生率的差异无统计学意义(P>0.05).结论 间苯三酚联合缩宫素静滴,可缩短产程,且不影响母婴安全.

Effects of phloroglucinol combined with oxytocin on labor progress and delivery outcome of primiparas needing induced labor

Objective To investigate the effect of phloroglucinol combined with oxytocin on labor progress, maternal and neonataloutcomes of primiparas needing induced labor.Methods Sixty cases of single-term primipara who needed induced labor in the ThirdPeople''s Hospital of Hefei from January 2019 to December 2020 were selected and randomly assigned into two groups. The controlgroup (30 cases) treated with oxytocin alone, while the observation group (30 cases) treated with oxytocin and phloroglucinol. The progress of labor, postpartum hemorrhage loss,the incidence of cervical or vaginal laceration, the third degree of amniotic fluid, the rate ofvaginal delivery, Apgar score for neonates were collected, and the data of two groups were compared and analyzed.Results The time of the first stage of labor and total stage of labor in the observation group were respectively (407.9±125.4) min and (450.5±131.0) min,which were significantly shorter than (663.3±218.2) min and (22.1±223.4) min in the control group, and the difference was statisticallysignificant (P<0.05). The differences of the vaginal delivery rate, the postpartum hemorrhage loss, the incidence of cervical and vaginallaceration, and the third degree of amniotic fluid between the two groups were not statistically significant (P>0.05).Conclusion The combination of phloroglucinol and oxytocin can shorten the labor process without affecting the maternal and infant safety.