灯心草的化学成分、药理活性及临床应用研究进展

灯心草Juncus effusus是灯心草科灯心草属植物，以其干燥茎髓或全草入药，在我国有着悠久的药用历史，灯心草主要含有9，10-二氢菲类、菲类、菲类二聚体类、芘类、甘油酯类、黄酮类、三萜类及甾体类等成分，具有镇静、抗癌、抗炎、抑菌、抗氧化、抑藻等生物活性，临床上常用于各类炎症、带状疱疹、甲状腺功能亢进及胃肠道症状的治疗。通过文献检索，对近40年来国内外相关文献进行归类、分析和总结，综述了灯心草的化学成分、药理活性及临床应用的研究进展，旨在为其进一步研究和开发利用提供参考。

Research progress on chemical constituents, pharmacological activities and clinical application of Juncus effusus

Juncus effusus, a kind of Juncus plant of Juncaceae family, with a long medication history in China, its dry stem or whole-plant have been used as medicine. It mainly contains 9,10-dihydrophenanthrenes, phenanthrenes, phenanthrene dimer, pyrenes, glycerides, flavonoids, triterpenes and steroids, which have a wide range of pharmacological activities, such as sedation, anti-cancer, anti-inflammatory, anti-bacterial, anti-oxidation, antialgal activities, and etc. In clinical practice, J. effusus is often used in treatment of various inflammation, herpes zoster, hyperthyroidism and gastrointestinal symptoms. Through literature search, the relevant literatures of J. effusus at home and abroad in recent 40 years were classified, analyzed and summarized. Chemical constituents, pharmacological activities and clinical application of J. effusus were reviewed in this paper, which will provide references for further research, development and utilization of this plant.