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胰十二指肠切除术后胃排空障碍危险因素的Logistic回归分析
引用本文:杜家文,宁武,裴东坡,黄林平,王正康. 胰十二指肠切除术后胃排空障碍危险因素的Logistic回归分析[J]. 中华肝胆外科杂志, 2009, 15(5). DOI: 10.3760/cma.j.issn.1007-8118.2009.05.019
作者姓名:杜家文  宁武  裴东坡  黄林平  王正康
作者单位:中日友好医院普外一科,北京,100029
摘    要:目的 分析胰十二指肠切除术后胃排空障碍的危险因素.方法 回顾性分析中日友好医院1994年1月至2008年1月间101例胰十二指肠切除术病例,以手术后是否发生胃排空障碍为因变量,对病人临床资料进行单因素及多因素非条件Logistic回归分析.结果 该组胃排空障碍发生率为27.7%(28/101),单变量分析结果表明手术方式、术中输血量、术后血糖、术后腹腔感染、术后胰胆肠瘘发生是胃排空障碍发生的危险因素.多因素Logistic回归分析结果表明,术后腹腔感染、手术方式、术中输血量、术后高血糖是胃排空障碍发生的独立危险因素,相对危险度(OR)分别为7.892、7.071、5.882和2.882.结论 术后并发腹腔感染、PPPD术后、术中输血量多、术后高血糖病人易发生胃排空障碍.

关 键 词:胰十二指肠切除术  胃排空障碍  危险因素

Analysis of risk factors for functional delayed gastric emptying after pancreaticoduodenectomy with Multivariate logistic regression
Abstract:Objective To study the risk factors for functional delayed gastric emptying(FDGE)after pancreaticoduodenectomy. Methods The clinical data of 101 cases undergoing pancreaticoduode-nectomy in our hospital from January 1994 to January 2008 were reviewed retrospectively. Results The incidence of FDGE was 27.7%(28/101). Univariate analysis showed PPPD,intraoperative blood transfusions,postoperative blood glucose, postoperative abdominal infection, postoperative pancreatic fistula and biliary fistula and intestinal fistula were the risk factors for gastric emptying after pancreati-coduodenectomy. Multivariate Logistic analysis regression revealed that postoperative abdominal infec-tion,PPPD,intraoperative blood transfusions,postoperative blood glucose were independent risk fac-tors(OR = 7. 892, 7. 071,5. 882 and 2. 882) of FDGE after pancreaticoduodenectomy. Conclusion Postoperative abdominal infection, PPPD, intraoperative blood transfusions, postoperative blood glu-cose can increase the incidence of FDGE.
Keywords:Pancreaticoduodenectomy  Delayed gastric emptying  Risk factors
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