622例HIV抗体筛查阳性病例采用免疫印迹试验确认结果分析

目的探讨HIV抗体ELISA筛查阳性与免疫印迹试验（WB）确证结果的关系,为HIV感染诊断提供科学依据。方法622例ELISA阳性标本与WB确证结果进行比较,采用SAS9.1进行数据描述统计和关联性分析。结果 364例确证为HIV-1抗体阳性,ELISA阳性与WB阳性符合率为58.52%。经spearman相关分析,ELISA S/Co比值与确证阳性密切相关。结论 ELISA筛查试验存在一定假阳性,高S/Co也并不代表HIV感染。

Analysis on HIV antibody screening positive and western blot test results among 622 cases

Objective To explore the relationship between the positive results from HIV antibody screening and results from Western Blot （ WB ） test, the study was conducted for providing scientific basis for the diagnosis. Methods The 622 positive samples of HIV antibody screened by ELISA test were confirmed by Western Blot test. All data were analyzed by SAS9.1. Resuits Among 622 positive samples tested by ELISA -screening test, 364 samples were confirmed to be positive by WB test with coincidence rate of 58.52%. The close relationship between S/CO value from ELISA and WB result was compared by spearman correlation analysis. Conclusion Some false positives do exist in the ELISA screening test. ELISA result with high S/CO values does not certainly mean HIV infection.