| 外阴阴道白假丝酵母菌病耐药机制研究进展 |
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| 引用本文： | 杨丽娜,祁文瑾,肖虹.外阴阴道白假丝酵母菌病耐药机制研究进展[J].昆明医学院学报,2012,33(3):143-146. |
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| 作者姓名： | 杨丽娜 祁文瑾 肖虹 |
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| 作者单位： | 昆明医学院第一附属医院妇产科,云南,昆明,650032 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 外阴阴道假丝酵母菌病(VVC)是妇女常见的外阴阴道炎症之一,随着抗生素和抗真菌药物的广泛应用,假丝酵母菌的菌种构成发生了一定变化.白假丝酵母菌的耐药株也逐渐增多.综述了白假酵母菌耐药机制,对寻找新的治疗策略和开发新的抗真菌药具有重要的指导意义.
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| 关 键 词： | 白假丝酵母菌 外阴阴道病 耐药机制 |
Research Progress in Mechanisms of Drug Resistance to Vulvovaginitis Caused by Candida Albicans |
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| YANG Li-na
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QI Wen-jin
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XIAO Hong.Research Progress in Mechanisms of Drug Resistance to Vulvovaginitis Caused by Candida Albicans[J].Journal of Kunming Medical College,2012,33(3):143-146. |
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| Authors: | YANG Li-na QI Wen-jin XIAO Hong |
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| Institution: | (Dept.of Gynecology and Obstetrics,The First Affiliated Hospital of Kunming Medical University, Kunming Yunnan 650032,China) |
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| Abstract: | The vulvovaginal candidiasis(VVC)is one of common vulvovaginitis of women,due to the abuse of antibiotics and antifungal drugs,the strains of pathogenetic candida have developed a certain changes.As the main pathogen of VVC,the strains of candida albican resistant to antifungal agent are increasing.The mechanisms of insensitivity to medicine involve function variation of multiple genes in the multi-level,so the investigation focusing on the mechanisms of drug insensitivity is helpful and meaningful to exploring new therapy strategies and invention of new antifungal drugs. |
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| Keywords: | Candida albican Vulvovaginitis Mechanisms of resistance |
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