脑死亡无偿器官捐献肝脏移植2例报道

目的总结并探讨脑死亡无偿器官捐献肝脏移植在我国临床实施的可行性.方法昆明市第一人民医院于2011年12月至2012年1月期间共完成2例脑死亡无偿器官捐献工作.2例供体确诊为脑死亡,应用机械通气、血管活性药物等治疗维持供体器官灌注.受体1男性,术前诊断乙肝后性肝硬化,肝功能失代偿,child-pugh C级,MELD评分29分;受体2男性,术前诊断乙肝后性肝硬化,原发性肝癌,child-pugh C级,MELD评分26分.结果 2例脑死亡供体均顺利无偿捐献肝脏,2例受体均顺利接受肝脏移植手术并康复出院,目前随访移植肝功能良好.结论脑死亡无偿器官捐献肝脏移植的临床实施顺利,可以在我国逐渐推广实行,对缓解我国目前器官短缺状况起到相当重要的作用.

Orthotopic Liver Transplantation from Donor after Brian Death (Report of 2 Cases)

Objective To summarize and explore the feasibility of implementing organ donation after brain death for liver transplantation in the clinic.Methods From December 2011 to January 2012,we completed two cases of unpaid organ donation after brain death.All donors were diagnosed as brain death,and maintained with mechanical ventilation and vasoactive drug therapy to guarantee the perfusion of donor organs.All recipients were male,the preoperative diagnosis was hepatitis B cirrhosis,liver decompensation,Child-Pugh class C,MELD score 29 points,and hepatitis B cirrhosis,primary liver cancer,Child-Pugh class C,MELD score 26 points.Results In these two cases,we successfully procured donor’s livers,and livers were successfully transplanted into all recipients,and working well during the follow-up period.Conclusion The implementation of liver transplantation using organs from brain death donors can gradually extended in our country,and is important to ease the shortage of organ pool.