| 芒果苷代谢产物1,3,6,7-四羟基三口酮的全合成 |
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| 引用本文： | 徐镇平,宋流东.芒果苷代谢产物1,3,6,7-四羟基三口酮的全合成[J].昆明医学院学报,2012,33(5):64-65. |
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| 作者姓名： | 徐镇平 宋流东 |
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| 作者单位： | 昆明医科大学药学院,云南,昆明,650500 |
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| 基金项目： | 云南省科技厅-昆明医科大学联合专项基金资助项目 |
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| 摘 要： | 目的 全合成芒果苷的一个主要代谢产物1,3,6,7-四羟基三口酮.方法 以2,4,5-三甲氧基苯甲酸为原料,参考文献方法,全合成1,3,6,7-四羟基三口酮.结果 成功合成1,3,6,7-四羟基三口酮,全合成总产率达25.73%.结论 以2,4,5-三甲氧基苯甲酸为原料,通过5步反应可成功合成1,3,6,7-四羟基三口酮,总产率较理想.
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| 关 键 词： | 芒果苷 代谢产物 1 3 6 7-四羟基三口酮 全合成 |
Total Synthesis of 1,3,6,7-Tetrahydroxyxanthone of Metabolites from Mangiferin |
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| XU Zhen-ping
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SONG Liu-dong.Total Synthesis of 1,3,6,7-Tetrahydroxyxanthone of Metabolites from Mangiferin[J].Journal of Kunming Medical College,2012,33(5):64-65. |
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| Authors: | XU Zhen-ping SONG Liu-dong |
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| Institution: | (School of Pharmaceutical Science,Kunming Medical University,Kunming Yunnan 650500,China) |
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| Abstract: | Objective To totally synthesize 1,3,6,7-tetrahydroxyxanthone of metabolites from mangiferin.Method 1,3,6,7-tetrahydroxyxanthone was totally synthesized from 2,4,5-trimethoxybenzate by the methods of references.Result 1,3,6,7-tetrahydroxyxanthone was obtained successfully,The total synthetic yield of 1,3,6,7-tetramethoxyxanthone is 25.73%.Conclusion 1,3,6,7-tetrahy droxy xanthone can be synthesized from 2,4,5-trimethoxybenzate total productive rate is idea. |
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| Keywords: | Mangiferin Metabolites 1 3 6 7-Tetrahydroxyxanthone Total synthesis |
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