皮肤基底细胞癌178例临床特征及组织病理学分析

目的 分析皮肤基底细胞癌的临床及组织病理学特征,提高诊断水平.方法 收集昆明医学院第四附属医院2004年7月至2011年12月门诊及住院皮肤基底细胞癌178例进行回顾性分析,所有病例病理标本采用常规石蜡切片、HE染色,部分病例常规诊断困难的加做免疫组织化学染色.Excel建立数据库,应用SPSS软件进行统计分析.结果 178例患者男性85例,女93例,女稍多于男性,年龄24～88岁,中位年龄63岁.结论 皮肤基底细胞癌患者首诊多数得不到正确诊断与及时、有效的治疗,导致病情进展,主要与恶性黑色素瘤、皮脂腺癌、鳞状细胞癌、毛发上皮瘤等鉴别.

Clinical and Histopathological Features of 178 Patients with Dermatological Basal Cell Carcinoma

Objective To analyze clinical and histopathological features of dermatological basal cell carcinoma for improving diagnostic level.Methods This study is a retrospective analysis.178 outpatients or inpatients with dermatological basal cell carcinoma from July 2004 to December 2011 were collected to review the clinical and histopathological features.Parafin section and HE staining were applied to all the cases,immunohistochemical staining was further applied to some cases with diagnostic difficulties.Excel was adopted to set up database and the data were analyzed by SPSS17.0.Result Of 178 cases,93 were male and 85 cases were female;The age of patients was 24～88,and the average age was 63.Conclusions Most patients with dermatological basal cell carcinoma could not get accurate diagnosis and timely treatment at the first diagnosis,which worsen their conditions.Ddermatological basal cell carcinoma should be differentiated from sebaceous gland carcinoma,malignant mela noma,epidermoid carcinoma etc.