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断血流提取工艺的研究
引用本文:刘芳,高元平,郑王巧,闫晓霞,武勇.断血流提取工艺的研究[J].长治医学院学报,2009,23(3):180-182.
作者姓名:刘芳  高元平  郑王巧  闫晓霞  武勇
作者单位:1. 长治医学院药学系,046000
2. 山西振东集团
摘    要:目的:利用正交试验设计优选提取断血流有效成分的工艺条件.方法:以醉鱼草皂苷Ⅵb的含量为指标,通过L9(34)正交试验设计,对提取工艺的加水量、煎煮时间、乙醇用量和乙醇浓度4个因素进行优选研究,以筛选出断血流的最佳提取工艺条件.结果:影响提取的主次因素为:煎煮时间>乙醇用量>加水量>乙醇浓度.优选得到的最佳提取工艺条件是用12倍量水煎煮3 h,提取液浓缩后加入1.7倍95%乙醇混匀,静置过夜,取上清液浓缩干燥即得.结论:本工艺条件科学合理,稳定可行,可有效保证产品质量.

关 键 词:断血流  醉鱼草皂苷Ⅵb  正交设计

Study on the Extraction of Duanxueliu Herb
Liu Fang,Gao Yuanping,Zheng Wangqiao,et al..Study on the Extraction of Duanxueliu Herb[J].Journal of Changzhi Medical College,2009,23(3):180-182.
Authors:Liu Fang  Gao Yuanping  Zheng Wangqiao  
Institution:Liu Fang,Gao Yuanping,Zheng Wangqiao,et al.Department of Pharmacology,Changzhi Medical College
Abstract:Objective:To optimize the extracting process of Duanxueliu herb by orthogonal design.Methods:An orthogonal design table L9(34)was used with the factors of water-adding amount,decoction time,ethanol concentration and the amount of ethanol.Results:The factors influencing the extraction efficiency were as follows:decoction time>the amount of ethanol>water-adding amount>ethanol concentration.The optimum extraction condition obtained was water,12 folds of the materials weight,decoction time 3 hours,95%ethanol as...
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