从针刺不同经穴对家兔胃黏膜保护作用探讨多经司控同一脏腑的规律

目的:探讨经脉腧穴与脏腑的特异关系.方法:将56只家兔随机分为7组,分别针刺不同经的穴位.硝酸还原酶法测定胃黏膜NO和NOS含量,放射免疫法测定PGE2、EGF含量,加权法分析各组综合效应.结果:(1)针刺足阳明经组与其余各组比较,能显著升高胃黏膜PGE2、EGF含量(P＜0.01);(2)针刺足阳明、足太阴经组与其余各组比较,能显著升高胃黏膜NO和NOS含量(P＜0.01);(3)针刺足阳明经组综合效应明显高于其余各组(P＜0.01);针刺足太阴经组综合效应明显高于模型组(P＜0.01).结论:多经司控同一脏腑具有一定的普遍性,但从作用强度和广度看又具有经脉的相对特异性;胃与足阳明经关系最为密切,足太阴经次之.

Study on regularity of multi-meridians controlling a same organ from the protective action of acupuncture at different acupoints on gastric mucosa in the rabbit

Objective To probe the special relation between the acupoint with zang - and fu -organs. Methods Fifty-six rabbits were randomly divided into 7 groups,which were treated respectively by acupuncture at acupoints of different channels. Nitric oxide (NO) level and nitric oxide synthase (NOS) activity in gastric mucosa were determined by the nitric acid reductase method,and prostaglandin E 2 (PGE 2) and epidermal growth factor (EGF) levels were measured by radioimmunoassay.The comprehensive effects were analyzed by weighting method. Results (1) The levels of PGE 2 and EGF in the gastric mucosa in the group treated by acupuncture at the Foot-Yangming Meridian increased significantly as compared with other groups ( P <0.01);(2) NO content and NOS activity in the gastric mucosa increased significantly in the Foot-Yangming Meridian group and the Foot-Taiyin Meridian as compared with other acupuncture groups ( P <0.01);(3) The comprehensive effect in the Foot-Yangming Meridian group was significantly higher than that in the other groups ( P <0.01),and in the Foot-Taiyin group was significantly higher than that in the model group ( P <0.01). Conclusion The principle of multi-meridians controlling a same organ has a certain universality. However,there is still a certain relative specificity of meridians in the intensity and the width of the effect;the stomach is related the most closely with the Stomach Meridian,the next,with the Foot-Taiyin Meridian.