北京市MSM HIV、梅毒和HSV-Ⅱ感染及影响因素分析

目的了解北京市男男性行为人群(MSM)的人类免疫缺陷病毒(HIV)、梅毒及单纯疱疹病毒Ⅱ型(HSV-2)的感染情况及影响因素。方法 2009年8-12月在北京市招募962名MSM进行一对一问卷调查,静脉取血进行HIV、梅毒和HSV-Ⅱ检测。结果在调查的962人中,最近6个月有91.27%(878/962)的人发生过肛交性行为,平均与3(范围1～413)名男性发生过性行为,有74.60%(655/878)在最近1次发生性行为时使用了安全套,49.66%(436/878)最近6个月在与男性肛交时每次都使用安全套;HIV感染率为6.34%(61/962),梅毒感染率为17.67%(170/962),其中活跃期梅毒感染率为9.88%(95/962),HSV-2特异性IgG抗体阳性率为5.30%(51/962);多因素Logistic回归分析显示:与HIV、活跃期梅毒、HSV-Ⅱ感染有统计学意义的因素分别是:非北京市户籍、近6个月与男性发生过性行为的人数>3人和活跃期梅毒;大专以下学历、HIV阳性和HSV-2阳性;年龄>25岁、大专以下学历、近6个月与男性发生过性行为的人数>3人、最近6个月与男性发生过无保护性行为、活跃期梅毒。结论北京市MSM人群HIV、梅毒及HSV-2感染率较高,应进一步加强有效的宣传教育和行为干预。

Prevalence and predictors of HIV,syphilis and herpes simplex type 2 virus(HSV-2) infections among the men who have sex with men(MSM)in Beijing

Objective To study the prevalence and predictors of human immunodeficiency virus(HIV),syphilis and herpes simplex type 2 virus(HSV-2) infections among MSM in Beijing.Methods The MSM were recruited with convenience sampling and investigated with a face-to-face questionnaire interview in Beijing ctiy between August to December,2009.Blood samples were collected to test HIV,syphilis,and HSV-2 infections.Results A total of 962 eligible MSM completed the inteview and blood sampling.The prevalence of HIV,syphilis,and HSV-2 infection was 6.34%(61/962),9.88%(95/962),and 5.30%(51/962),respectively.Multivariate logistic regression analyses showed that HIV infection was associated with non-Beijing residence,having more than 3 sex partners in the latest 6 months,and recent syphilis infection.The syphilis imfection was associated with having the education level lower than college,with HIV infection,and posititve for HSV-2.The HSV-2 infection was associated with at age of more than 25 years,with lower education than college,having more than 3 sex partners in the latest 6 months,having unprotected sex in the past six month,and recent syphilis infection.Conclusion The MSM in Beijing had high infection rates of HIV,syphilis,and HSV-2 and effective education and behavior intervention should be conducted.