平均血小板质量与降钙素原在儿童川崎病诊断中的应用价值

目的 探讨平均血小板质量(mean platelet mass,MPM)与降钙素原(procalcitonin,PCT)在儿童川崎病(kawasaki disease,KD)诊断中的应用价值。方法 分别测定117例急性期川崎病患儿的MPM与血小板计数(PLT)、平均血小板体积(MPV)、血小板体积分布宽度(PDW)以及降钙素原(PCT)的水平,且与126例正常对照组儿童进行比较,并同时比较各指标的阳性率及相关性。结果 ①川崎病儿童急性期MPM水平显著低于对照组,PLT,MPV及PCT水平显著高于对照组(P<0.05,α=0.05); 两组PDW水平比较差异无统计学意义(P>0.05,α=0.05)。②MPM阳性率明显高于其它指标(P<0.05,α=0.05)。结论 MPM对儿童川崎病诊断具有较好的应用价值,可作为一项实验室辅助诊断指标在临床推广。

Clinical Value of Mean Platelet Mass and the Procalcitonin in Diagnosis of Kawasaki Disease

Objective To investigate the clinical value of mean platelet mass(MPM)and the procalcitonin(PCT)in diagnosis of Kawasaki disease(KD).Methods A Total of 117 children with KD in the acute stage and 126 children of the control group were detected respectively andcompared each other.The indexes contain MPM,PLT,MPV,PDW and PCT.Meanwhile,the comparison of each index's positive rate and the linear correlation analysis of each index were conducted.Results ①The level of MPM of the KD group was significant lower than that of the control group,PLT,MPVand PCT significant higher than those(P<0.05,α=0.05).The differenceof PDW between the two groups was no statistical significance(P>0.05,α=0.05).②The positive rate of the MPM was significant higher than that of the other indexes(P<0.05,α=0.05).Conclusion The detection of MPM is helpful to the diagnosis of KD and can be used as an indicatorof KD clinically.