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Multilobated B cell lymphoma (Pinkus variant) with isolated muscular localization in a patient with systemic sclerosis: a case report
Authors:M Parma  G Sita  A Guffanti  F Bianchi  M Colombi  L Baldini
Institution:(1) Servizio Autonomo di Ematologia Diagnostica, Centro G. Marcora, Istituto di Scienze Mediche dell' Università degli Studi, Pad. Granelli, Ospedale Maggiore IRCCS, via F. Sforza 35, I-20122 Milan, Italy, IT;(2) Divisione di Medicina I, Ospedale "Fatebenefratelli e Oftalmico", Milan, Italy, IT;(3) Servizio di Anatomia Pathologica, Ospedale "Fatebenefratelli e Offalmico", Milan, Italy, IT
Abstract: The association of systemic sclerosis (SSc) and non-Hodgkin's lymphoma (NHL) is a rare event whose pathogenesis remains to be clarified. We describe a case of NHL in a patient with SSc, in whom the NHL was particular in terms of clinical presentation (primitive muscle and bone involvement) and histologic type (large multilobated B-cell variant). The lymphoma was clinically aggressive but responded well to therapy. Surveillance for the development of "atypical" NHL is suggested in SSc cases. Received: 21 September 1995 / Accepted: 23 February 1996
Keywords:  Systemic sclerosis  non-Hodgkin's lymphoma
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