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Eruption of palmoplantar pustular psoriasis in patient treated with anti-androgen therapy for prostate cancer and aggravation of lesions after statin treatment |
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| Authors: | Aldona Pietrzak Jerzy Mosiewicz Grażyna Chodorowska Anna Brzozowska Anna Michalak-Stoma Justyna Szumiło Marcin Trojnar Dorota Krasowska Bartłomiej Wawrzycki Kinga Franciszkiewicz-Pietrzak Wojciech Polkowski Torello Lotti |
| Affiliation: | 1. Chair and Department of Dermatology, Venereology and Paediatric Dermatology, Medical University of Lublin, 20-080, Lublin, Poland 2. Chair and Department of Internal Medicine, Medical University of Lublin, 20-080, Lublin, Poland 3. Chair and Department of Oncology, Medical University of Lublin, 20-080, Lublin, Poland 9. St. John’s Cancer Center, 20-090, Lublin, Poland 4. Chair and Department of Clinical Pathomorphology, Medical University of Lublin, 20-080, Lublin, Poland 8. St. John’s Cancer Center, 20-090, Lublin, Poland 5. Department of Surgery, Medical University of Lublin, 20-080, Lublin, Poland 6. Chair and Department of Oncologic Surgery, Medical University of Lublin, 20-080, Lublin, Poland 7. Chair and Department of Dermatology and Venereology, University of Rome“G. Marconi”, Rome, Italy |
| Abstract: | The article focuses on the eruption of palmoplantar pustular psoriasis, which was documented in a 53-year-old man diagnosed with prostate cancer with bone metastases. This clinical finding was made during routine hormone therapy and palliative radiotherapy. The local improvement in skin lesions was achieved following administration of topical ointments and the use of UVA 311 nm radiation therapy. The management of prostate cancer in this subject resulted in malaise, onset of diabetes mellitus and increased concentration of serum lipids. Interestingly, a few days after the statin treatment was initiated, the intensive pustule eruption was observed as well as severe pain and burning sensation in the palms and soles. The dermatological treatment led to significant improvement. The patient is still receiving oncological therapy and is monitored by dermatologists on a regular basis. |
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