NPTS联合透明质酸钠生物胶治疗开角型青光眼

目的:回顾总结非穿透性小梁切除联合透明质酸钠生物胶植入及丝裂霉素应用治疗开角型青光眼的疗效。方法:对20例24眼开角型青光眼施行非穿透性小梁切除手术,术中巩膜床植入透明质酸生物胶及应用丝裂霉素,术后随访12～36mo,观察眼压、视力、前房角、滤过泡等情况。结果:术后1,2,3a时眼压分别为16.32±5.25,17.28±5.70,18.26±5.20mmHg,与术前眼压35.52±7.6mmHg相比明显下降(P<0.01)。术后视力达到或高于术前水平22眼,视力下降2眼。术中、术后均未出现浅前房及前房炎症反应。24眼均有功能型滤过泡。结论:非穿透性小梁切除联合透明质酸钠生物胶植入及丝裂霉素应用能安全、有效地治疗开角型青光眼。

Observation of the effect of nonpenetrating trabeculectomy combined with hyaluronic acid biologic glue implantation to treat open angle glaucoma

AIM:To analyse the efficiency of nonpenetrating trabeculectomy(NPT) combined with hyaluronic acid biologic glue implantation and mitomycin C(MMC) usage in the treatment of open angle glaucoma·METHODS: A retrospective analysis was made of 20 cases(24 eyes) with open angle glaucoma which had undergone NPT combined with hyaluronic acid biologic glue implantation and MMC usage under the layer of scleral valve.All the cases were followed up for 12-36 months.The intraocular pressure(IOP),visual acuity,anterior chamber depth,and filtering bleb were observed·RESULTS:The IOP was decreased from 35.52±7.6mmHg preoperatively to 16.32±5.25,17.28±5.70,18.26±5.20mmHg postoperatively in 1 year;2,3 years respectively(P<0.01).Visual acuity was at or above the preoperative level in 22 eyes,vision decreased in 2 eyes.There were no intraoperative or postoperative shallow anterior chamber and anterior chamber inflammation.All 24 eyes had functional bleb·CONCLUSION:NPT combined with hyaluronic acid biologic glue implantation and MMC usage is safe and effective in the management of open angle glaucoma.