| 医用生物玻璃和磷灰石材料对小鼠骨髓细胞微核率的影响 |
| |
| 引用本文： | 李新生,马明福,李练兵,张其清.医用生物玻璃和磷灰石材料对小鼠骨髓细胞微核率的影响[J].北京生物医学工程,1999,18(4):243-244. |
| |
| 作者姓名： | 李新生 马明福 李练兵 张其清 |
| |
| 作者单位： | 1. 重庆市计划生育科学研究所,重庆,400020
2. 中国医学科学院生物医学工程所,天津,300192 |
| |
| 摘 要： | 采用啮齿类动物微核试验对医用生物玻璃材料和磷灰石材料的浸提液进行诱变性检测，结果显示，每一材料浸提液的浸提原液，１／５和１／１０倍浸提液３个剂量组诱导的多染红细胞微核率与溶剂对照组比较，无显著性差异，Ｐ〉０．０５，表明各剂量线的浸提液无诱发小鼠骨髓细胞微核增加作用。
|
| 关 键 词： | 生物玻璃 磷灰石 小鼠骨髓细胞 微核试验 |
The Effect of Medical Bioglass and Phosphatic Rock on Micronucleus in Bone Marrow of Mice |
| |
| Li Xinsheng,Ma Mingfu,Li Lianbing,Zhang Qiqing.The Effect of Medical Bioglass and Phosphatic Rock on Micronucleus in Bone Marrow of Mice[J].Beijing Biomedical Engineering,1999,18(4):243-244. |
| |
| Authors: | Li Xinsheng Ma Mingfu Li Lianbing Zhang Qiqing |
| |
| Abstract: | The mutagenicity of medical materials of bioglass and phosphatic rock was studied by doing mouse marrow micromuleus test.The results showed that all extracts from medical materials (bioglass and phosphatic rock) of three groups (original extract,extracts of 1/5 and 1/10 of the original one) did not produce significant statistical differences between each tested and contrast group ( P >0 05).In this experiment, it was proved that medical materials (bioglass and phosphatic rock) would not induce increase of micronucleus. |
| |
| Keywords: | Bioglass Phosphatic rock Mouse bone marrow Micronuclei test |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
