两种方法治疗肝癌疗效比较

目的 比较手术治疗和超声引导下经皮射频消融治疗肝癌的临床疗效.方法 78例肝癌患者随机分为两组,手术组和射频消融组各39例,手术组患者常规进行开腹手术治疗,射频消融组患者使用超声引导经皮射频消融进行治疗,对比两组治疗效果.结果 所有患者经治疗后均进行随访,手术组1、2、3年生存率与射频消融组差异均无统计学意义（均P＞0.05）；中央型、≤3cm肝癌患者1、2、3年生存率比较：射频消融组明显高于手术组（x2 =4.819、4.815、4.919,均P＜0.05）.结论 超声引导下经皮射频消融治疗中央型、≤3 cm肝癌患者的疗效明显,近期疗效优于手术治疗.

Comparative study of two ways to treat liver cancer

Objective To compare the clinical effects of surgical treatment and ultrasonic guidance percutaneous radiofrequency ablation（PRFA） therapy in the treatment of liver cancer.Methods 78 patiens with live cancer were randomly divided into the operation group and PRFA group,each group had 39 patients.The operation group was treated with traditional open surgery,the PRFA group was treated with radiofrequency ablation.The clinical effect was compared between the two groups.Results All patients were followed up after therapy,the 1,2,3-year survival rate between operation group and PRFA group had no significant differences （all P 〉 0.05）,but in the patients whose tumor were central type and samller than 3cm,the 1,2,3-year survival rate of PRFA group were significantly higher than operation group（x2 =4.819,4.815,4.919,all P 〈 0.05）.Conclusion Ultrasonic guidance percutaneous radiofrequency ablation therapy in the treatment of liver tumor is effective,and the effect is better than operation group,especially for the patients with central type tumor and the tumor samller than 3cm.