全肠外营养在晚期肿瘤中应用价值探讨

目的探讨晚期肿瘤患者全肠外营养支持的临床价值。方法通过多项指标评价38例晚期肿瘤患者的营养状况和免疫功能，38例患者均存在营养不良和免疫功能低下，将病人分为二组，治疗组22例，行颈内静脉置管给予全肠外营养；对照组16例则行口服饮食和(或)常规外周静脉营养。3周后再测定各项指标并行统计学处理。结果治疗组治疗前和治疗组治疗后与对照组治疗后的营养指标、免疫功能指标均明显改善(均P<0.05)，治疗组生存期明显延长(P<0.01)。结论全肠外营养可以改善晚期肿瘤患者的营养状况，提高免疫力，改善生活质量，延长生存期。

Effect of total parenteralnutrition for advanced-stage cancer patients

Objective　To evaluate the effect of total parente ral nutrition(TPN) maintenance on patients with advanced cancer.Methods 　38 patients with advanced cancer in severe malnutrition and immune dys function,were divided into therapy group (T group)and control group(C group).T group (22 cases)was given TPN maintenance by catheterization in internal jugula r vein and C group was given oral diet and (or) routine intravenous fluids.Sever al data used to assess the nutritional status and the immune function were detec ted at the beginning of the research and three weeks later. Results 　Data regarding to nutritional status and immune function showed a sign ificant difference between T group and C group,as well as between before and aft er three weeks′s treatment in T group.(P<0.05).The survival time of T group was prolonged much more than that of C group (P<0.05).Conclusions　 TPN maintenance is beneficial to improve the nutritional status and the immune function of patients with advanced cancer,as well as to promote the life quality and prolong the survival time.