Depot naltrexone decreases rewarding properties of sugar in patients with opioid dependence期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Depot naltrexone decreases rewarding properties of sugar in patients with opioid dependence

Authors:	Daniel?D.?Langleben author-information" > author-information__contact u-icon-before" > mailto:langlebe@upenn.edu" title=" langlebe@upenn.edu" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Elliot?L.?Busch,Charles?P.?O’Brien,Igor?Elman

Affiliation:	(1) Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA;(2) Philadelphia Veterans Administration Medical Center, Philadelphia, PA, USA;(3) Bedford Veterans Administration Medical Center, Bedford, MA, USA;(4) Department of Psychiatry, Cambridge Health Alliance, Harvard Medical School, Boston, MA, USA

Abstract:	Background Opioid neurotransmission mediates hedonic value of sweet tastants; their intake may be exaggerated by the consumption of exogenous opioids (e.g., opioid dependence). Sweet Taste Test (STT) is a validated quantitative instrument assessing taste perception and hedonic features of sugar (sucrose) using a randomized and double-blind administration at five different sucrose concentrations ranging from 0.05 to 0.83 M.

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