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Acute renal failure due to ureteral obstruction in a kidney transplant recipient with Candida albicans contamination of preservation fluid
Authors:M. Veroux  D. Corona  G. Giuffrida  M. Gagliano  T. Tallarita  A. Giaquinta  D. Zerbo  A. Cappellani  P.F. Veroux
Affiliation:Department of Surgery, Transplantation and Advanced Technologies, Vascular Surgery and Organ Transplant Unit, University Hospital of Catania, Catania, Italy
Abstract:Abstract: Reported rates of positive preservation fluid cultures range from 5% to 23%, with fungi accounting for 2–10% of all positive cultures. We report the case of a kidney transplant recipient who received a graft with preservation fluid contaminated by Candida albicans , who developed acute renal failure due to ureteral obstruction by fungus balls. The patient was treated with voriconazole with complete restoration of graft function. This rare clinical entity demonstrates the usefulness of pre-transplant cultures of preservation fluid, in order to identify a group of patients who could benefit from antifungal prophylaxis therapy and thereby prevent the need for graft nephrectomy.
Keywords:kidney transplantation    Candida albicans    fungal infection    fungus balls    preservation fluid contamination
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