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非甲~庚型肝炎患者中TTV感染的调查
引用本文:林佳佳,谢雯,何忠平,刘安澜,段雪飞.非甲~庚型肝炎患者中TTV感染的调查[J].实用肝脏病杂志,2003,6(2):80-82.
作者姓名:林佳佳  谢雯  何忠平  刘安澜  段雪飞
作者单位:100011,北京市地坛医院
摘    要:目的了解TTV在我院非甲-庚型肝炎患者中的感染状况。研究TTV感染对非甲-庚型肝炎临床表现的影响,探讨TTV在病毒性肝炎中的致病作用。方法采用聚合酶链反应(PCR)斑点杂交法对我院108例非甲-庚型肝炎患者血清标本进行TTV DNA检测。结果非甲-庚型肝炎患者TTV DNA阳性率为14.8%(16/108),急、慢性肝炎及重型肝炎患者中TTV DNA的检出率无统计学差异。TTV阳性组与TTV阴性组肝脏临床及生化指标无显著性差异。结论TTV可能并非是导致肝脏功能损害的真正病原。

关 键 词:输血传播病毒  非甲-庚型肝炎  聚合酶链反应

A study of TTV infection in patients with non A-G hepatitis
Lin Jiajia,Xie Wen,He Zhongping,et al..A study of TTV infection in patients with non A-G hepatitis[J].Journal of Clinical Hepatology,2003,6(2):80-82.
Authors:Lin Jiajia  Xie Wen  He Zhongping  
Affiliation:Lin Jiajia,Xie Wen,He Zhongping,et al. Beijing Ditan Hospital,Beijing 100011,China
Abstract:Objective To study TTV infection in patients with non A - C hepatitis, its clinical process and its role in pathogene-sis of viral hepatitis.Methods 108 serum samples from non A- C hepatitis in our hospital were detected for TTV DNA with dot- blot hybridization. Results The positive rate of TTV in non A- C hepatitis was 14.8%(l6/108)and no statistical difference among acute, chronic and severe hepatitis. There were no obvious differences in clinical or biochemical features of liver disease beween the patients of non A- C hepatitis with TTV DNA positive and with negative.Conclusion TTV is unlikely to be a true pathogen inducing non A- C hepatitis.
Keywords:TTV Non A to G hepatitis Polymerase chain reaction
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