EHF特异性IgG抗体检测及病人与ABO血型系统关系研究

研究表明,EHF病人不同病程、病期及不同临床表现其特异性IgG抗体GMT各异,随着病程延长、病期推移,病情加重,GMT逐渐升高,说明体液免疫反应强弱与病情轻重,特别是临床各期的表现有关(P<0.05)。正常人群EHF隐性感染率较低,GMT也很低,认为该病单份血清特异性IgG抗体>1∶320者,结合临床症状即可作出早期诊断。流行期前后人群隐性感染率无显著性差异(P>0.05),EHF的发病与人血型系统无关。

Study on the Correlation between Detected EHF-Specific gG Antibody and ABO Blood Type System

The result of investgation showed that the patients with different course and different phase of the disease and different clinical manifestation varied from serum specific IgG antibody -GMT.As following prolongation of the course and dhase of the disease, having exasperate, the level of GMT- antibody has graduatdolly g rising.This phenomenna could be explained by the situation of the Humoral-immuno reaction correlated.to severity of the disease, especially to different clinlcal features. Among normal population in the local the latent infection rate of EHF is lower, therefore, the GMT is also lower.In general speaking, the patient, whose serum titter of specific IgG antibody is in 1:320,and associated with their clinical manifestations , could be diagnosed. Early There was no obvious difsirence in latent infection in the population before anp later in prevalence, and no relationship between prevalence and ABO blood type was found.