The evaluations of concentrations IL-5 and IL-6 in toxoplasmosis |
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Authors: | Matowicka-Karna Joanna Kemona Halina Panasiuk Anatol |
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Institution: | Zak?ad Laboratoryjnej Diagnostyki Klinicznej, Bia?ystok. matowic@amb.edu.pl |
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Abstract: | The immune system, its cellular and humoral response, is engaged by the host organism to fight against parasitic invasions. The group examined consisted of 38 women aged 19-39 years infected with Toxoplasma gondii. The diagnosis was established basing on serologic examination. Blood for analysis was collected before antiparasitic treatment. Control group consisted of 40 healthy women aged 18-46 years. The concentrations of IgM, IgG and IgE were assayed using a set of VIDAS (bioMerieux) according to the ELFA method. The concentrations of IL-5, IL-6 were assayed using a set of Quantikine human (R&D Systems) according to the immunoenzymatic methods with labeled antibodies. The present study revealed that in toxoplasmosis the concentration of IgE, IL-5 and IL-6 contents in blood serum was 2-times higher, than in healthy controls. |
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