我院呼吸科住院患者抗菌药物使用调查与分析

目的:了解我院2010年呼吸科住院患者抗菌药物使用的合理性.方法:采用回顾性分析方法,随机抽取呼吸科出院病历100份,对抗菌药物的用药方案、联合用药、用药起始时间、病原学检查、用药频度等情况进行统计并评价其合理性.结果:100例呼吸科住院患者使用抗菌药物比例为97％,其中二联用药比例占56％.用药频度前三位的药物分别为左氧氟沙星、头孢米诺和克林霉素.病原学检查率为71％,平均用药天数为14天.结论:呼吸科住院患者的抗菌药物使用基本合理,但仍存在联合用药依据不足、时间依赖性抗菌药给药间隔不当、肾功能不全患者抗菌药物未减量导致不良反应等不合理用药情况,需要加强培训和监督管理.

Survey Analysis of Antibiotic Utility in Respiratory Department of Our Hospital

Objotivo： To investigate the antibiotic utility in the respiratiory department of our hospital. Methods： Retrospective analysis method was used, 100 medical records were randomly selected from the respiratory department. Antibiotic regimens, combined drugs, starting time and frequency of antibiotics and pathogenic test were studied. Results： 97% of respiratory patients used antimicrobial agents with 56% of the patients having a combination of two antibiotics. The top three most frequently used antibiotics were levofloxacin, cefminox and clindamycin. Frequency of pathogenic examination was 71%. The average duration of antibiotic treatment was 14 days. Conclusion： Antibiotic use in our respiratory department is reasonable, but there are still problems, such as insufficient evidence for combined antibiotic therapy, inappropriate dosing interval for time-dependent antibiotics and no dose adjustment for patients with renal insufficiency, which require strengthened training and supervision.