针刺足少阳胆经五输穴脑fMRI研究

目的 采用fMRI观察针刺足少阳胆经五输穴的脑功能区激活情况。方法 选取男性健康青年志愿者12名, 针刺右侧足少阳胆经五输穴, 在静息段与针刺段交替采集fMRI图像, 获得数据通过random effect法对数据行组分析, 以P <0.05的像素构成统计参数图, 即实验任务脑激活区, 按Talairach坐标行解剖定位, 获得试验任务激活的脑区。结果 受试者脑激活区包括左侧眶回(BA11)、双侧顶上小叶(BA7)、右侧颞上回(BA22)。负激活区包括右侧舌回(BA18)、右侧扣带回(BA24)、双侧顶上小叶(BA7)、右侧颞下回(BA20)。结论 针刺足少阳胆经五输穴可影响边缘系统、听觉系统、语言、记忆等。针灸叠加针刺引起对应的脑功能区变化是大脑传导通路重新整合与分配的结果。

Cerebrum fMRI study on the acupucture of Five Shu Points of gall bladder meridian of Foot-Shaoyang

Objective To explore the activation of brain regions during the acupuncture of Five Shu Points of gall bladder meridian of Foot-Shaoyang. Methods Twelve young male healthy volunteers were selected, the right gall bladder meridian Five Shu Points were acupunctured. The fMRI images were obtained in resting stage and acupuncture stage. Data were analyzed through random effect method, statistical parametric mapping was composed with pixels of P <0.05. According to the Talairach coordinate for anatomic localization, Experimental task activated brain regions were obtained. Results The activation area of brain included left orbitofrontal cortex (BA11), bilateral superior parietal lobule (BA7), right superior temporal gyrus (BA22). Negative active region included right lingual gyrus (BA18), right cingulate gyrus (BA24), bilateral superior parietal lobule (BA7), right inferior temporal gyrus (BA20). Conclusion The stimulates of the gall bladder Five Shu acupoints can affect the functions of limbic system, the auditory system, language, memory, etc. Superposition of acupuncture can induce corresponding changes in brain areas of the brain pathway re-integration and distribution.