阿托伐他汀钙片和血脂康片治疗冠心病合并高脂血症的效果对比分析

目的：分析比较阿托伐他汀钙片和血脂康片治疗冠心病合并高脂血症的临床效果。方法选取66例冠心病合并高脂血症患者为研究对象，随机分为两组，各33例。观察组患者给予阿托伐他汀钙片治疗，对照组患者给予血脂康片治疗。结果两组患者治疗前血脂各项指标差异均无统计学意义；治疗后两组甘油三酯（TG）均无明显变化（ P ＞0．05）；治疗后两组总胆固醇（TC）和低密度脂蛋白胆固醇（LDL-C）均较治疗前降低（ P ＜0．05），两组高密度脂蛋白胆固醇（HDL-C）均较治疗前升高（ P ＜0．05）；治疗后观察组TC、LDL-C和HDL-C指标变化均优于对照组（ P ＜0．05或P ＜0．01）。结论阿托伐他汀钙片治疗冠心病合并高脂血症的疗效确切，能够使TC和LDL-C下降，HDL-C升高，值得临床推广应用。

Comparison between the curative effect of atorvastatin and Xuezhikang in the treatment of coronary heart disease combined with hyperlipidemia

Objective To compare the curative effect of atorvastatin and Xuezhikang in the treatment of coronary heart disease （ CHD） combined with hyperlipidemia .Methods Sixty-six patients with CHD combined with hyperlipidemia were selected and were randomly divided into experimental group （ n =33） and control group（ n =33）.The experimental group was given atorvastatin ,and the control group was given Xuezhikang .Results The indexes of blood lipid of the two groups before treatment showed no significant difference and TG of the two groups had no significant change after treatment （ P 〉0.05）, but TC and LDL-C were significantly re-duced（ P 〈0.05）,and HDL-C of the two groups were significantly increased （ P 〈0.05）.All the indexes of TC, LDL-C and HDL-C of observation group were better than that of the control group （ P 〈0.05or P 〈0.01）.Conclution Atorvastatin in the treatment of CHD combined with hyperlipidemia has obvious curative effect and can reduce low density lipoprotein cholesterol and serum total cho -lesterol.