乳腺癌肺转移的放化疗评价

目的以乳腺癌肺转移患者进行放、化疗评价。方法68例乳腺癌肺转移病人中8例为单发转移灶，行局部放疗合并化疗；60例为多发转移灶，给予CMF、CAF、CAP三阶梯方案化疗。结果8例单发转移灶放疗后CR3例，PR3例，合并化疗后CR62．5％，PR37．5％；60例多发转移灶病人先予CMF方案，CR28．3％，PR23．3％，缓解率51．7％，无效病人依次使用CAF、CAP方案，CR分别为11．6％，19．0％。三方案毒性反应依次增加。结论放疗对局部转移灶的控制是重要的，CMF应为乳腺癌肺转移的首选方案，CMF、CAF、CAP依次使用有利于提高完全缓解率，延长生存期。

The evaluation of the effect of radiotherapy and chemotherapy on lung metastases from breast cancer

To evaluate the effect of radiotherapy and chmotherapy on lung rnetas tases from breast cancer. Methods Sixty eight cases with lung matastasis included 8 cases with sin gle metastases who had received radiotherapy and chemotherapy, 60 cases with multiple metastases received chemotherapy only. Their project was CMF,CAF,CAP in turn. Results Eight cases with single metastasis received radiotherapy, 3 cases were CR, 3 cases were PR, then combined with chemotherapy, CR 62. 5 %, PR 37. 5 % Sixty cases with mulliple metastases recelved CMF, CR 28. 3%,PR 23. 3%, then the other cases were treated with CAF and CAP in turn .CR 11. 6% and 19. 0%. Toxicity of the three projects enhanced in turn. Conclusion Radiotherapy is important to single rnetastasis patients, CMF should be the cho1ce for treating lung metastasis from breast cancer,CMF, CAF,CAP used 1n turn will be beneficial to these patients.