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Transforming growth factor beta and connective tissue growth factor are involved in the evolution of nevus of Nanta |
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| Authors: | Keida Tomoko Hayashi Nobukazu Kawakami Michiko Kawashima Makoto |
| Affiliation: | Department of Dermatology, Seibo Hospital, Tokyo, Japan. |
| Abstract: | We report a 59-year-old Japanese male with nevus of Nanta on the face. Histological examination revealed a nest of nevus cells in the dermis and ossification beneath the nevus. Positive staining for transforming growth factor-beta and connective tissue growth factor suggested the involvement of these growth factors in the ossification of nevus of Nanta. |
| Keywords: | nevus of Nanta osteoma cutis cutaneous bone formation transforming growth factor‐β (TGF‐β) connective tissue growth factor (CTGF) |
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