The relevance of plasma lipid changes with cardiovascular drug therapy |
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| Authors: | B F Johnson M A Danylchuk |
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| Affiliation: | University of Massachusetts Medical School, Worcester. |
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| Abstract: | Evidence is reviewed that thiazide diuretics increase plasma levels of triglycerides and LDL-cholesterol, and that most beta-blockers increase triglycerides and depress HDL-cholesterol. By contrast, indapamide, pindolol, and calcium channel blockers have little effect, and alpha 1-blockers and alpha 2-stimulants may improve the HDL- to LDL-cholesterol ratio. |
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