甲状腺功能亢进症的药物治疗

抗甲状腺药物(ATD)治疗的最佳方案要从药物的选择、具体剂量、给药方式、服药疗程、是否合用左旋甲状腺素(L-T4)、免疫抑制剂及其他影响患者缓解率的因素等多方面综合考虑.除妊娠期妇女外,目前大多数学者将甲硫咪唑(MMI)列为治疗甲状腺功能亢进症(甲亢)的首选药物.药物具体起始剂量可根据患者甲状腺的大小、甲亢病情的严重程...

Drug therapy of hyperthyroidism

The choice of drug,dosage, administration, course of treatment, the combination of L-T4,the application of immunosuppressive agent, and other factors which can influence the remission rate should be considered in the treatment of hyperthyroidism with antithyroid drugs (ATD). Currently, most researchers consider methimazole(MMI) as the first choice used to treat hyperthyroidism, except for the women during pregnancy. The starting dose should be according to the size of thyroid nodules and the severity of the disease. The duration of therapy was 12 to 18 months. Titration regimens have been widely accepted to be the standard therapy for hyperthyroidism nowadays. Should L-T4 be combined with ATD and choice of optimal medication time is controversial. Further clinical research is needed to conform their safety and efficiency for the widely use of immunosuppressive agents.