| 脂肪细胞线粒体功能与肥胖 |
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| 引用本文： | 周云,肖新华.脂肪细胞线粒体功能与肥胖[J].国际内分泌代谢杂志,2011,31(2). |
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| 作者姓名： | 周云 肖新华 |
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| 作者单位： | 南华大学第一附属医院内分泌科,衡阳,421001 |
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| 基金项目： | 国家自然科学基金，湖南省教育厅青年基金 |
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| 摘 要： | 线粒体主要存在于能量需求高、代谢强的组织,被认为是细胞的"动力工厂",为细胞的代谢活动提供能量.肥胖的发生主要是脂质积聚过多,而脂肪细胞线粒体是脂肪酸β氧化的场所之一,脂肪细胞线粒体的脂肪酸氧化功能对于维持脂肪细胞内甘油三酯代谢有重要作用,其功能失调与肥胖的关系成为新的研究热点.Abstract：Mitochondria are usually described as the "powerhouse unit" of the cell, which exist in tissues with a high energy demand and a high metabolic activity, and provide energy for the metabolic activity of cell. More lipid accumulation can lead to obesity. Mitochondria are the main sites of fatty acid β oxidization which are very important to adipocyte triglyceride metabolism. The relationship between mitochondrial dysfunction and obestiy has become the new research derection.
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| 关 键 词： | 脂肪细胞 线粒体 脂代谢 肥胖 |
Adipocyte mitochondrial function and obesity |
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| ZHOU Yun,XIAO Xin-hua.Adipocyte mitochondrial function and obesity[J].International JOurnal of Endocrinology and Metabolism,2011,31(2). |
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| Authors: | ZHOU Yun XIAO Xin-hua |
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| Abstract: | Mitochondria are usually described as the "powerhouse unit" of the cell, which exist in tissues with a high energy demand and a high metabolic activity, and provide energy for the metabolic activity of cell. More lipid accumulation can lead to obesity. Mitochondria are the main sites of fatty acid β oxidization which are very important to adipocyte triglyceride metabolism. The relationship between mitochondrial dysfunction and obestiy has become the new research derection. |
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| Keywords: | Adipocytes Mitochondria Lipid metabolism Obesity |
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