| 乳腺癌易感基因1的临床研究进展 |
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| 引用本文： | 张杰,佟仲生. 乳腺癌易感基因1的临床研究进展[J]. 国际肿瘤学杂志, 2011, 38(3): 206-209. DOI: 10.3760/cma.j.issn.1673-422X.2011.03.014 |
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| 作者姓名： | 张杰 佟仲生 |
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| 作者单位： | 乳腺癌防治教育部重点实验室,天津市肿瘤防治重点实验室,天津医科大学附属肿瘤医院乳腺肿瘤内科,300060 |
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| 摘 要： | 乳腺癌易感基因1(BRCA1)突变与乳腺癌、卵巢癌等许多癌症发生密切相关.近年来越来越多的研究提示,在化疗疗效、放疗敏感性及手术效果等方面,BRCA1突变乳腺癌与其他乳腺癌相比有显著差异.BRCA1的研究为其今后在临床上的应用提供了方向.
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| 关 键 词： | 基因,BRCA1 乳腺肿瘤 治疗 预后 |
Clinical progression of breast cancer susceptibility gene BRCA1 |
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| ZHANG Jie,TONG Zhong-sheng. Clinical progression of breast cancer susceptibility gene BRCA1[J]. Journal of International Oncology, 2011, 38(3): 206-209. DOI: 10.3760/cma.j.issn.1673-422X.2011.03.014 |
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| Authors: | ZHANG Jie TONG Zhong-sheng |
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| Abstract: | BRCA1 is a breast cancer susceptibility gene,which related to breast cancer,ovarian cancer and other cancers.The occurrence of breast cancer is related to gene mutation.In recent years,more and more researches indicated some clinical characteristics of breast cancer relevant to BBCA1,such as the reaction to chemotherapy,radiotherapy and operation. This review will provide guidance for future application of BRCA1 in clinic by introducing the clinical progression of it. |
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| Keywords: | Genes,BRCA1 Breast neoplasms Therapy Prognosis |
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