| 干扰素调节因子3在病毒性肝炎发病机制中的研究进展 |
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| 引用本文： | 闫芳,郜玉峰,尹华发. 干扰素调节因子3在病毒性肝炎发病机制中的研究进展[J]. 国际流行病学传染病学杂志, 2011, 38(2): 108-110. DOI: 10.3760/cma.j.issn.1673-4149.2011.02.010 |
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| 作者姓名： | 闫芳 郜玉峰 尹华发 |
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| 作者单位： | 安徽医科大学第一附属医院感染病科,合肥,230032 |
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| 摘 要： | IFN调节因子3(IRF-3)是IRF家族成员之一,是对IFN基因表达起主要作用的调节因子,与病毒感染时IFN基因的表达水平密切相关,特别是在HBV和HCV感染方面具有重要作用.此文就IRF-3与病毒性肝炎的研究进展作了综述.
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| 关 键 词： | 肝炎,病毒性,人 干扰素调节因子3 免疫调节 |
Research progress of interferon regulatory factor 3 in the pathogenesis of viral hepatitis |
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| YAN Fang,GAO Yu-feng,YIN Hua-fa. Research progress of interferon regulatory factor 3 in the pathogenesis of viral hepatitis[J]. International Journal of Epidemiology and Infectious Disease, 2011, 38(2): 108-110. DOI: 10.3760/cma.j.issn.1673-4149.2011.02.010 |
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| Authors: | YAN Fang GAO Yu-feng YIN Hua-fa |
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| Abstract: | Interferon regulatory factor 3 (IRF-3) is a member of the IRF family which plays a major role in gene expression of IFN regulatory factors, and is closely related to the level of IFN gene expression in condition of viral infection, especially in the pathogenesis of hepatitis B virus and hepatitis C virus. The research progress of IRF-3 in the patho-genesis of viral hepatitis are reviewed. |
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| Keywords: | Hepatitis,viral,human Interferon regulatory factor 3 Immunomodulation |
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