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端粒耗损与心血管疾病
引用本文:施宇光,于景翠,刘芳萍. 端粒耗损与心血管疾病[J]. 国际遗传学杂志, 2011, 34(2). DOI: 10.3760/cma.j.issn.1673-4386.2011.02.004
作者姓名:施宇光  于景翠  刘芳萍
作者单位:1. 150000,哈尔滨,东北农业大学兽医药理教研室;150081,哈尔滨医科大学附属第二医院科研实验中心
2. 哈尔滨医科大学附属第二医院科研实验中心,150081
3. 东北农业大学兽医药理教研室,哈尔滨,150000
基金项目:哈尔滨医科大学附属第二医院青年基金
摘    要:心血管疾病一直被认为是与年龄相关的退行性疾病,端粒随年龄增长而变短,是细胞老化的标志.最近,越来越多的研究表明端粒长度缩短与心血管疾病发生发展有关.该文仅就端粒耗损与心血管疾病相关性的研究进展作一综述,旨在为今后心血管疾病的预防和治疗提供新的思路.
Abstract:
Cardiovascular disease (CVD)has been considered as an age-related degenerative diseases. Telomere shortens with age, that is a sign of cell senescence. Currently, more and more researches show that the shortening of telomere length is correlated with the occurrence and progress of cardiovascular diseases. This article reviewed the studies on the relationship of telomere loss and cardiovascular diseases in order to provide new ideas for the prevention and treatment of cardiovascular diseases.

关 键 词:端粒耗损  心血管疾病

Telomere loss and cardiovascular disease
SHI Yu-guang,YU Jing-cui,LIU Fang-ping. Telomere loss and cardiovascular disease[J]. International JOurnal of Genetics, 2011, 34(2). DOI: 10.3760/cma.j.issn.1673-4386.2011.02.004
Authors:SHI Yu-guang  YU Jing-cui  LIU Fang-ping
Abstract:Cardiovascular disease (CVD)has been considered as an age-related degenerative diseases. Telomere shortens with age, that is a sign of cell senescence. Currently, more and more researches show that the shortening of telomere length is correlated with the occurrence and progress of cardiovascular diseases. This article reviewed the studies on the relationship of telomere loss and cardiovascular diseases in order to provide new ideas for the prevention and treatment of cardiovascular diseases.
Keywords:Telomere loss  Cardiovascular disease
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