| 间充质干细胞与肿瘤生物治疗 |
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| 引用本文： | 李彩荣,凌斌. 间充质干细胞与肿瘤生物治疗[J]. 国际肿瘤学杂志, 2011, 38(4): 254-256. DOI: 10.3760/cma.j.issn.1673-422X.2011.04.005 |
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| 作者姓名： | 李彩荣 凌斌 |
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| 作者单位： | 安徽省立医院分子医学实验室,合肥,230001 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 间充质干细胞(MSC)具有低的免疫原性和特异的组织趋向性,并且取材方便、体外扩增能力强,因而成为理想的工程细胞.修饰MSC使其表达特定的抗癌分子,或者将其作为靶向抗癌的一个载体成为近几年肿瘤生物治疗研究的热点.MSC在肿瘤生物治疗方面的应用显示着很大的潜力.
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| 关 键 词： | 间充质干细胞 趋化因子 肿瘤 生物疗法 |
Mesenchymal stem cells and tumor biological treatment |
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| LI Cai-rong,LING Bin. Mesenchymal stem cells and tumor biological treatment[J]. Journal of International Oncology, 2011, 38(4): 254-256. DOI: 10.3760/cma.j.issn.1673-422X.2011.04.005 |
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| Authors: | LI Cai-rong LING Bin |
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| Abstract: | Mesenchymal stem cells (MSCs) are oonsidered as the ideal engineering cells because of their accesibility, their in vitro amplification capacity, low immunogenicity and their tendency toward the tissues. Modification of these cells to express specific anti-cancer molecules or to be a vector for targeted anticancer therapy become a hotspot of biological therapy in recent years. The continual development of MSC study shows great advantage as biological treatment on tumor. |
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| Keywords: | Mesenchymal stem cells Chemokines Neoplasms Biological therapy |
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