滑石粉尘对陶瓷工人的健康效应

目的：探讨滑石粉尘对陶瓷工人呼吸系统疾病发生发展的影响。方法：采用历史前瞻性队列研究，全体队列成员按是否接触矽尘和滑石尘分为不接尘组，矽尘组和滑石尘矽尘组，运用优势比（Odds Ratios,OR)方法作计算分析。结果：滑石尘矽尘组工人的非恶性呼吸道疾病（如尘肺）和肺心病的死亡危险度与矽尘组类似，但其癌症的死亡危险度，特别是肺癌死亡比不接尘组明显超高，OR＝4．73，P＜0．01）。结论：认为颗粒型滑石可能是瓷厂工人中致肺癌因子，滑石粉尘对矽肺发病也有明显的促进作用。

Health effects of talc exposed workers in pottery factories

Objective To explore the health effects of talc dust on the occurrence and development of the respiratory diseases in talc exposed pottery workers.Methods It was designed as a cohort study. All the study objects were divided into three groups: non-dust-exposed workers, silica-dust-exposed workers, and talc-silica-exposed workers. Odds ratios( OR) was used for analysis. Results The risk of non-malignant respiratory diseases (in particular silicosis) and pulmonary heart diseases were similar to that of the talc-silica-exposed workers and the silica-dust-exposed workers. The risk of lung cancer for the talc-silica-exposed workers appeared to be increased significantly than that of non-dust-exposed workers, OR = 4.73, P<0.01. Conclusion The findings showed that the paiti-culate talc might be a factor causing lung cancer among the pottery workers and might promote the occurrence of the silicosis.