| 曲安奈德结膜下注射对兔眼巩膜创伤愈合过程的影响 |
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| 引用本文： | 夏娣,傅少颖,崔静.曲安奈德结膜下注射对兔眼巩膜创伤愈合过程的影响[J].黑龙江医学,2008,32(8). |
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| 作者姓名： | 夏娣 傅少颖 崔静 |
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| 作者单位： | 哈尔滨医科大学第五临床医学院,黑龙江,大庆,163311;哈尔滨医科大学第一临床医学院,黑龙江,哈尔滨,150001 |
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| 摘 要： | 目的观察曲安奈德结膜下注射对家兔眼巩膜穿通伤创口愈合的治疗作用。方法12只有色家兔,左眼为实验组,右眼为对照组。双眼均制成巩膜穿通伤模型,清创缝合后左眼结膜下注射曲安奈德20mg/0.5 mL,右眼结膜下注射平衡盐液0.5 mL,均为1次/2周。于术后28 d处死家兔,取眼球行HE染色和PCNA免疫组化检查,对比巩膜创口愈合情况。结果实验组与对照组相比PCNA阳性细胞计数有统计学意义(P<0.05)。结论曲安奈德结膜下注射于创口周围,有利于巩膜穿通伤创口的愈合。
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| 关 键 词： | 曲安奈德 结膜下注射 巩膜穿通伤 |
Subconjuctival Injection of Triamcinolone Acetonide for Treatment of Experimental Sclera Traumatic |
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| XIA Di,FU Shao-ying,CUI Jing.Subconjuctival Injection of Triamcinolone Acetonide for Treatment of Experimental Sclera Traumatic[J].Heilongjiang Medical Journal,2008,32(8). |
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| Authors: | XIA Di FU Shao-ying CUI Jing |
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| Abstract: | Objective To determine the triamcinolone acetonide for the treatment of sclera wound in a model of rabbits sclera trauma.Methods Sclera trauma was induced in pigmented rabbits by performing a scaeral laceration followed by rapair.Twelve eyes were treated with subconjunctival injection of 20mg triamcinolone acetonide every twice week.Twelve eyes were treated subconjunctival injection of compound sodium chloride as contrast.Results Both the quantities and percentage of eyes were significantly lower in eyes treated with suconjunctival injection of triamcinolone acetonide.Conclusion The treatment of subconjunctival injection of triamcinolone acetonide was a stimulative in scleral wound concrescence. |
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| Keywords: | Triamcinolone acetonide Subconjunctival injection Sclera wound |
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