| 维胺酯-β-环糊精包合物的研究 |
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| 引用本文： | 孙淑英,张晓菁.维胺酯-β-环糊精包合物的研究[J].沈阳药科大学学报,1997,14(3):157-160. |
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| 作者姓名： | 孙淑英 张晓菁 |
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| 作者单位： | 沈阳药科大学药学系，沈阳志鹰制药厂 |
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| 摘 要： | 应用３因素８水平的均匀设计方法，优化出维胺酯－β－环糊精包合物最佳制备条件，所得包合物的包合率为９９．３％，其表观稳定常数为１３９４Ｍ－１．
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| 关 键 词： | 维胺酯 β－环糊精 包合物 均匀设计 |
Study on Retinamido Ester β Cyclodextrin Inclusion Complexes |
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| Sun Shuying,Zhang Xiaoqing,Yang Huaping,Liu Xiulan,Zhang Jinsong.Study on Retinamido Ester β Cyclodextrin Inclusion Complexes[J].Journal of Shenyang Pharmaceutical University,1997,14(3):157-160. |
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| Authors: | Sun Shuying Zhang Xiaoqing Yang Huaping Liu Xiulan Zhang Jinsong |
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| Abstract: | In this study 3 factors and 8 levels of conditions for the preparation of the retinamido ester β CD inclusion complex were selected by the uniform design.An optimal condition was established.Under the optimal conditions the inclusion complex was prepared.The drug,including rate was 99 3%.The apparently stability constant of the inclusion complex was 1294 M -1 . |
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| Keywords: | retinamido ester β cyclodextrin inclusion complex uniform design |
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