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改良二袖套法大鼠原位肝脏移植150例报告
引用本文:秦磊,高广勇,余斌,钱海鑫.改良二袖套法大鼠原位肝脏移植150例报告[J].苏州大学学报(自然科学版),2005,25(1):77-80.
作者姓名:秦磊  高广勇  余斌  钱海鑫
作者单位:苏州大学附属第一医院普外科 江苏苏州215006 (秦磊,高广勇,余斌),苏州大学附属第一医院普外科 江苏苏州215006(钱海鑫)
摘    要:目的通过对二袖套法大鼠原位肝移植手术方法的改进,提高大鼠肝移植动物模型的稳定性。方法采用改良的二袖套法施行大鼠原位肝移植150例,观察术后并发症及存活率。结果手术成功率由最初的30%提高到后来的97%,2周存活率由最初的0%提高到后来的90%。结论改进的大鼠原位肝移植方法操作简便,手术成功率高,重复性好,提高了大鼠肝移植动物模型的稳定性。

关 键 词:肝移植  大鼠  模型  移植  同种
文章编号:1673-0399(2005)01-0077-04
修稿时间:2004年3月19日

Experience After 150 Cases of Rat Orthotopic Liver Transplantation
QIN Lei,GAO Guang-yong,YU Bing,et al.Experience After 150 Cases of Rat Orthotopic Liver Transplantation[J].Suzhou University Journal of Medical Science,2005,25(1):77-80.
Authors:QIN Lei  GAO Guang-yong  YU Bing  
Abstract:Objective To increase the stability of rat orthotopic liver transplantation models effectively by improving the surgical procedures. Methods 150 cases of rat orthotopic liver transplantation were performed with the modified two-cuffed technique, and the effects of various perioperative treatment factors and surgical techniques on the survival rate and viability were observed. Results The 24 hours and 2 week survival rates were 97% and 90% respectively. Conclusion The modified two-cuffed methods is convenient and easy to repeat. It can enhance the stability and increase survival rate of rat orthotopic liver transplantation models.
Keywords:liver transplantation  rat  model  transplantation  homologous
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