血清胆碱酯酶活性与肝病的相关性研究

目的探讨血清胆碱酯酶活性与肝病的相关性。方法检测肝病患者血清胆碱酯酶（ChE）活性及肝纤维化标志物HA水平，分析两者的相关性。结果肝病患者肝实质损害越重，肝纤维化程度越高，血清ChE活性下降越明显，HA值增加越明显，两者呈负相关。结论血清ChE活性测定是评估肝病患者肝细胞损害程度和肝组织纤维化的灵敏指标。

RELATION OF THE CHOLINESTERASE(CHE)ACTIVITY AND HEPATOPATH

Objective To investigate the relation between serum cholinesterase (ChE) and hepatopathy. Methods the serum ChE and the serum markers of fibrosis activity with hepatopathy were detected and analyzed the association between them. Results The more hepatic cells injured, the severe the degree of fibrosis and the much decrease of serum ChE, the much increase of the HA level, as it showed a negative relation. Conclusion Serum ChE is the sensitive marker for elevating the degrees of hepatic tissue injury and fibrosis.