流行性出血热73例死亡病例临床分析及治疗探讨

<正> 流行性出血热(简称出血热),是一种危害人民健康严重的自然疫源性疾病,由于其病理生理变化复杂,临床经过凶险,加上目前尚无特异性诊断方法和病因治疗,病死率较高。十年前国内文献报导在2.6～19.2％。近十年来虽经广大医务工作者的努力,不断改进治疗措施,但病死率仍在3.85～8.9％,而且省级医院病死率仍超过10％。我院自1972年元月至1981年12月共收治出血热516例,死亡73例,病死率14.14％。

A CLINICAL ANALYSIS OF 73 CASES DIED OF EPIDEMIC HEMORRAGIC FEVER

From January, 1971 to December, 1981, 516 cases of epidemic hemorrhagic fever were admitted in our hospital. Among them 73 cases died, the fatality rate was 14.1％. With exclusion of the 11 cases dying within 24 hours after admission, the correction fatality rate was 12.01％. Fifty-two cases died of acute renal failure, 15 cases died of shock. Prevention and management of acute renal failure should be the key points to decrease the fatality rate of the epidemic hemorrhagic fever. Shortening the period of shock, applying diuretic early, and application of catharsis therapy in severe cases were the principle of managment of acute renal failure. To prevent and manage of hemorrhage should be also the important means to decrease the fatality rate. In our cases, there were 27 enterorrhagia cases and 11 intracranial hemorrhage cases. Apart from application of hemostatic, anticoagulant therapy in early stage should be a method to manage the hemorrhage.