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Effects of IL-1beta and IL-6 on tissue-type plasminogen activator expression in vascular endothelial cells |
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| Authors: | Larsson Pia Ulfhammer Erik Karlsson Lena Bokarewa Maria Wåhlander Karin Jern Sverker |
| Institution: | a Clinical Experimental Research Laboratory, Department of Emergency and Cardiovascular Medicine, Sahlgrenska University Hospital/Östra, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden b Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden c Clinical Development AstraZeneca R&D, Mölndal, Sweden |
| Abstract: | |
| Keywords: | t-PA Tissue-type plasminogen activator IL Interleukin HUVEC Human umbilical vein endothelial cells NF-κB Nuclear factor κB MAPK Mitogen activated protein kinase PAI-1 Plasminogen activator inhibitor-1 TNF-α Tumor necrosis factor-α EMSA Electrophoretic mobility shift assay sIL-6R Soluble interleukin-6 receptor |
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