肺结核空洞切除术在空洞性肺结核治疗中的临床应用研究

目的 照机械抽样法随机分为两组,Ⅰ组15例,用标准化疗方案治疗,Ⅱ组28例,用标准化疗方案治疗的同时行肺结核空洞切除术.结果 Ⅱ组患者治疗后咯血停止者占85.7％(24/28),痰菌阴性者占96.4％ (27/28),退热者占92.9％(26/28),均显著高于Ⅰ组患者的13.3％(2/15)、33.3％(5/15)、26.7％(4/15),两组比较差异有统计学意义(P＜0.01).Ⅰ组患者治疗后咯血停止时间、痰菌转阴时间及退热时间分别为( 10.2±1.1)、(8.3±1.2)、(9.1±1.1)个月,均显著长于Ⅱ组患者的(6.3±1.2)、(4.5±1.3)、(5.3±1.2)个月,两组比较差异有统计学意义(P＜0.05).结论 肺结核空洞切除术应用于空洞性肺结核的治疗,可显著提高疗效,缩短治疗时间,成为空洞性肺结核的治疗手段之一.

Clinical application research of tuberculous cavity resection in cavitary tuberculosis

Objective To study the clinical applications value of tuberculous cavity resection in cavitary tuberculosis.Methods Forty-three cases of patients with cavitary tuberculosis were selected and divided into 2 groups by mechanical sampling method,15 cases in group Ⅰ were given standard chemotherapy regimen,28 cases in group Ⅱ were given standard chemotherapy regimen combined with tuberculous cavity resection.Results After treatment,the proportion of haemoptysis ending in group Ⅱ was85.7％(24/28),the proportion of negative sputum bacteria was 96.4％(27/28),and the proportion of antfebrile was 92.9％(26/28),which were higher than those in group Ⅰ 13.3％(2/15),33.3％(5/15),26.7％(4/15)].There were significant differences between two groups(P＜ 0.01 ).But after treatment,the time needed for improving symptoms in group Ⅰ ( 10.2 ± 1.1 ),(8.3 ± 1.2 ),(9.1 ± 1.1 ) months]were significantly longer than those in group Ⅱ (6.3 ± 1.2 ),(4.5 ± 1.3 ),( 5.3 ± 1.2) months],and there were significant differences between two groups (P＜0.05).Conclusion The tuberculous cavity resection in treatment for cavitary tuberculosis can significantly improve the curative effect,and shorten the period of treatment.