新生儿先天性食管闭锁术后早期营养途径比较

目的 比较新生儿先天性食管闭锁术后早期三种营养途径的临床应用效果.方法 将81例新生儿先天性食管闭锁术后早期按不同的营养支持方式分为肠内营养组(27例)、肠外营养组(30例)及肠内外营养组(24例),根据术后一般情况及生化指标进行分析.结果 肠内营养组、肠外营养组、肠内外营养组除了禁食时间分别为(7.2±9.8)、(7.1±9.3)、(7.4±9.6)d]外,热量摄入、体重变化、体重、不耐受例数、住院天数比较差异均有统计学意义(P＜0.01),优劣为肠内外营养组＞肠内营养组＞肠外营养组,差异有统计学意义(P＜0.05).肠内营养组、肠外营养组、肠内外营养组除了C反应蛋白分别为(7.0±2.4)、(6.4±1.8)、(6.2±1.3) mg/L]外,总蛋白、白蛋白、血红蛋白等其他各项检验指标比较差异均有统计学意义(P＜0.01),优劣为肠内外营养组＞肠内营养组＞肠外营养组,差异有统计学意义(P＜0.05).结论 新生儿先天性食管闭锁术后早期肠内外营养更符合食物消化、吸收的生理过程,值得在临床中推广.

Comparison of early nutrition channels in postoperative neonatal congenital esophageal atresia

Objective To compare the clinical effects of 3 kinds of early nutrition channels to the postoperative neonatal congenital esophageal atresia.Methods Nutritional support in different ways,81 cases of congenital esophageal atresia were divided into enteral nutrition group (group A),parenteral nutrition group (group B) and enteral-parenteral nutrition group (group AB).Analysis was conducted according to the general situation and postoperative biochemical parameters.Results There were statistically differences in all conditions (P ＜ 0.01 ) excepted fasting time (7.2 ± 9.8 ),(7.1 ± 9.3 ),(7.4 ±9.6) d ] in group A,B,AB,advantages and disadvantages:group AB ＞ group A ＞ group B,the difference was statistically significant (P ＜ 0.05).In group A,B,AB,in addition to C-reactive protein (7.0 ± 2.4),(6.4 ± 1.8 ),(6.2 ± 1.3 ) mg/L ],the other of the biochemical differences were statistically significant (P ＜0.01),advantages and disadvantages:group AB ＞group A ＞group B,the difference was statistically significant (P ＜ 0.05).Conclusions Enteral and parenteral nutrition in postoperative neonatal congenital esophageal atresia is more sutiable for food digestion and absorption.It is worth in clinical promotion.