| 后程同期小野加量放射治疗鼻咽癌的临床研究 |
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| 引用本文： | 甘赞辉,李济培,王洪乾,何晓洪. 后程同期小野加量放射治疗鼻咽癌的临床研究[J]. 实用癌症杂志, 2010, 25(1): 49-52 |
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| 作者姓名： | 甘赞辉 李济培 王洪乾 何晓洪 |
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| 作者单位： | 广西玉林市红十字会医院肿瘤放疗科,537000 |
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| 摘 要： | 目的探讨后程同期小野加量放射治疗鼻咽癌的临床疗效及副作用。方法对经放疗（D，50Gy）后疗效为PR、SD、PD的250例鼻咽癌患者，随机分为常规分割放疗纽（对照组）及后程同期小野加量放射治疗组（研究组）。结果治疗结束时，研究组和对照组原发灶CR、PR率分别为33．60％、66．40％和22．40％、77．60％（P〈0．05），放疗后3～6个月，研究组和对照组原发灶CR、PR率分别为42．40％、57．60％和29．60％、70．40％（P〈0．05）;研究组和对照组1、3、5年原发灶局部控制率分别为97．60％、83．20％、79．20％和95．20％、75．20％、68．00％（P〈0．05）；研究组和对照组的1、3、5年生存率分别为97．60％、76．80％、59．20％和93．60％、67．20％、46．40％（P〈0．05）;研究组急性放射反应与对照组比较无明显差异（P〉0．05），晚期放射损伤相同．结论对放射治疗肿瘤消退较小鼻咽癌患者，予后程同期小野加量放射治疗的疗效高于常规放疗．且毒副作用无明显增强．
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| 关 键 词： | 鼻咽癌 放疗 |
Later Course Small Field Boost Radiotherapy for Nasopharyngeal Carcinoma |
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| GAN Zan-hui,LI Ji-pei,WANG Hong-qian,et al.. Later Course Small Field Boost Radiotherapy for Nasopharyngeal Carcinoma[J]. The Practical Journal of Cancer, 2010, 25(1): 49-52 |
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| Authors: | GAN Zan-hui LI Ji-pei WANG Hong-qian et al. |
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| Affiliation: | GAN Zan-hui,LI Ji-pei,WANG Hong-qian,et al. Department of Radiation Oncology,Yulin City Red Cross Hospital,Yulin,537000 |
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| Abstract: | Objective To explore the curative effects and side effects of later course small field boost radiotherapy for Nasopharyngeal carcinoma (NPC). Methods 250 NPC patients were randomized into later course small field boost radiotherapy group (the study group) and conventional radiotherapy group (the control group) after 50 Gy radiotherapy.Results After the treatment,the CR and PR rates in the study group and the control group was 33.60%,66.40% and 22.40%,77.60% respectively (P<0.05).The CR and PR rates of the t... |
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| Keywords: | Nasopharyngeal neoplasm Radiotherapy |
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